OSH 5303 Advanced Tox (7)

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Assignment Content


  1. The assignment for this unit consists of 2 parts. Part A is an annotated bibliography and Part B is a Research Paper. Please read the instructions for each part and follow the directions carefully.
    Part A:
    As a safety manager, consider chemicals that you would likely find at a facility that can cause nephrotoxicity. Research three scientific journal articles that discuss research findings on these chemicals as they relate to nephrotoxicity.
    Summarize each article and their research findings in your own words. Also, include in your summary what type of facility would this chemical be found and what type of control could be used to protect employees from the chemical. Credit will not be given for reiterating the abstract.
    APA formatting must be implemented. Select three scientific research articles from the CSU library. Each article summary must be a minimum of 200 words.
    Part B:
    In the assigned reading for this unit, you learned about various chemicals that induce reproductive toxicity. Flame retardants are used in products such as household furniture, plastics, and electronic and electrical equipment. Flame retardants are supposed to increase safety by reducing the flammability of items. However brominated flame retardants can cause reproductive toxicity. Research a specific brominated flame retardant such as tetrabromobisphenol A (TBBPA), tetrabromophthalic anhydride, dibromoneopentylglycol, or brominated styrene that can cause reproductive toxicity and apply it to the research paper as directed below.
    Develop a research paper that includes the following:

    • Background information on the toxicant, its use, and routes of exposure,
    • the process by which this toxicant causes reproductive toxicity and the concentration of exposure,
    • briefly summarizing the reproductive system may be necessary to discuss how the toxicant causes reproductive toxicity, ways exposure to the toxicant might be limited, treated, and/or effects reversed, and
    • recent research findings (within the last five years) on this chemical.

    The paper should be a minimum of two pages in length, not counting the title and reference pages, and written in APA format with proper in-text citations and references. The paper should utilize at least three credible sources that include at least one peer-reviewed journal article published within the last five years.

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