NURS 6521 George Mason University Advanced Pharmacology Nursing Essay

ASSIGNMENT

PHARMACOTHERAPY FOR GASTROINTESTINAL AND HEPATOBILIARY DISORDERS

In this Assignment, you examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan.

RESOURCES

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.

oChapter 64, “Drugs for Peptic Ulcer Disease” (pp. 589–597)

oChapter 65, “Laxatives” (pp. 598–604)

oChapter 66, “Other Gastrointestinal Drugs” (pp. 605–616)

oChapter 80, “Antiviral Agents I: Drugs for Non-HIV Viral Infections” (pp. 723–743)

Chalasani, N., Younossi, Z., Lavine, J. E., Charlton, M., Cusi, K., Rinella, M., . . . Sanya, A. J. (2018). The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver DiseasesLinks to an external site.. Hepatology, 67(1), 328–357. Retrieved from https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/…

This article details the diagnosis and management of nonalcoholic fatty liver disease. Review this article to gain an understanding of the underlying pathophysiology as well as the suggested pharmacotherapeutics that might be recommended to treat this disorder.

To Prepare:

Review the case study assigned by your Instructor for this Assignment

Reflect on the patient’s symptoms, medical history, and drugs currently prescribed.

Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors, such as pregnancy, drugs, or a psychological disorder.

Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.

Write a 1-page paper that addresses the following:

Explain your diagnosis for the patient, including your rationale for the diagnosis.

Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.

Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

DC is a 46-year-old female who presents with a 24-hour history of RUQ pain.  She states the pain started about 1 hour after a large dinner she had with her family.  She has had nausea and on instance of vomiting before presentation.

PMH:

Vitals:

• HTN
• Temp:  98.8oF
• Type II DM
• Wt:       202 lbs

Gout

Ht:        5’8”

DVT – Caused by oral BCPs

• BP:       136/82
• HR:       82 bpm
• Current Medications:

Notable Labs:

Lisinopril 10 mg daily

WBC:                13,000/mm3

HCTZ 25 mg daily

Total bilirubin:    0.8 mg/dL

Allopurinol 100 mg daily

Direct bilirubin:  0.6 mg/dL

Multivitamin daily

Alk Phos:           100 U/L

AST:                   45 U/L

ALT:                   30 U/L

Allergies:

Latex

Codeine

Amoxicillin

PE:

Eyes: EOMI

HENT: Normal

GI:Nondistended, minimal tenderness

Skin:Warm and dry

Neuro: Alert and Oriented

Psych:Appropriate mood

End of Case